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刘志明
 发表时间:2013-06-26 15:45:00 点击次数:0

Zhiming Liu刘志明  教授、博导

分子发育生物学

Email zhiming.liu@csuft.edu.cn;    1356078903 @qq.com

  


 

学习经历:

1994-1998年,美国德克萨斯州理工大学分子生物学专业,博士后 

1990-1994年,美国德克萨斯州理工大学分子生物学专业,博士学位

1988-1990年,美国华盛顿大学渔业科学专业,硕士学位

1978-1982年,上海海洋大学水产养殖学专业,学士学位

主要工作经历

2014-至今,经济林培育与保护省部共建教育部重点实验室特聘教授

2014-至今,湖南省长沙市外专局引智工作专家咨询委员会主任

2014-至今,湖南省外专局引智工作专家咨询委员会专家委员

2013-至今,入选湖南省“百人计划”,中南林业科技大学特聘教授

2009-2011,宁波大学“包玉刚讲座教授”

2009-至今,美国东新墨西哥州立大学教授

2005-2009SIGMA XI国际科学研究会,美国东新墨西哥州立大学分会主席

2004-至今,西安交通大学客座教授

成果与专长:

 本人多年来利用世界上先进的生物技术与分子生物学方法(如: 细胞培养,基因克隆以及转基因)从事动植物发育方面的研究。主持和参与了多项国内外重大科研项目。关于STAR蛋白,COX与前列腺素受体基因的研究处于国际领先水平,研究成果得到国际同行的认可。固醇类激素合成,激素受体作用,STARCOX以及前列腺素受体基因表达对卵母细胞发育的调控等方面的论文发表在著名的国际刊物,:<<分子及细胞内分泌学>><<生殖生物学>><<内分泌学>><<固醇类化学及分子生物学>><<美国科学院研究进展>>。曾获美国德克萨斯州理工大学博士后研究论文比赛第一名。所指导的博士后, 研究生及本科生参加了六十多次国际学术会议并作专题报告,九篇学生论文在会议上获奖。除了科研外,担任分子生物学, 细胞生物学,生物技术与基因工程课程的教学。

目前在中南林业科技大学我们进行珍稀濒危植物珙桐和水松种子败育的分子机制,以及油茶脂肪酸合成酶基因功能等方面的研究。细胞分化机理、基因表达调控,以及转基因方面的研究是解决生物医学领域,农林业生产中面临的许多技术难题的基础,与医药,农林业生产、生物资源的利用关系极为密切,对人类健康以及农林牧渔业生产等都将产生深远的影响。

代表性论文和专利

1.       Wang, J.Y., Tan, X.F., Zeng, Y.L., Long, H.X., Mei, F.F., Chen, H.P., and Z. Liu. Cloning and expression analysis of a fatty acid hydroperoxide lyase gene from Camellia oleifera. Journal of Nanoscience and Nanotechnology, 2014, submitted.

2.       Wang, J.Y., Tan, X.F., Long, H.X., Zeng, Y.L., Mei, F.F., Chen, H.P., and Z. Liu. Cloning and expression analysis of an aldehyde dehydrogenase gene from Camellia oleifera. Journal of Nanoscience and Nanotechnology, 2014, submitted.

3.       Xu, G.B., Liu, X.S., Liang, W.B., and Z. Liu. Megasporogenesis and female gametophyte development in critically endangered Chinese swamp cypress  Glyptostrobus pensilis.  Botany, 2014, submitted.

4.       Elder, D., Liu, Z., Wells, R.A., and M.F. Shaughnessy.  Current educational concerns in 2013 and beyond.  International Journal of Academic Research, Part B, 2013, 5(3)7-10.

5.       Sun, X., He, Y.L., Xu, N.J., Xia, Y.M., and Z. Liu.  Isolation and identification of two strains of pathogenic bacteria and their effects on the volatile metabolites of Gracilariopsis lemaneiformis (Rhodophyta).  Journal of Applied Phycology, 2012, 24:277-284.

6.       Liu, Z., Su, X.R., Li, T.W., Pan, D.D., Sena, J., and J. Dhillon.  Molecular cloning and expression of prostaglandin F2a receptor isoforms during ovulation in the ovarian follicles of Xenopus laevis.  Prostaglandins and Other Lipid Mediators, 2010, 93: 93-99.

7.       Dhillon, J.K., Su, X.R., and Z. Liu.  Effects of RU 486 on cyclooxygenase-2 gene expression, prostaglandin F2a synthesis and ovulation in Xenopus laevis.  General and Comparative Endocrinology, 2010, 165:78-82.

8.       Sena, J. and Liu, Z.  Expression of cyclooxygenase genes and production of prostaglandins during ovulation in the ovarian follicles of Xenopus laevis.  General and Comparative Endocrinology, 2008157:165-173.

9.       Su, X.R., Lu, Z.M., Li, T.W., Liu, Z. and P.K., Chien.  Analysis of isozymes related to energy metabolism of adult Tegillarca granosa.  Journal of Agricultural Biotechnology, 2007, 4(2):163-166.

10.   Kumakura, N., Sena, J., Wright, S., Gott, M., Patino, R. and Z. Liu.  Molecular cloning and roles of cyclooxygenases in amphibian ovulation.  New Mexico Journal of Science, 2006, 44:227–247.

11.   Liu, Z., Pandey, N.R. and M. Plasterer.  Isolation and purification of a membrane-associated progesterone receptor in amphibian oocytes.  New Mexico Journal of Science, 2003, 43(1):51-67.

12.   Liu, Z.  Phylogenetic relationships of the living chimaeroid fishes based on characters of brain and cranial nerves.  New Mexico Journal of Science, 2002, 41(1):1-24.

13.   Murphy, B.D., Lalli, E., Walsh, L.P., Soh, J., Liu, Z., Stocco, D.M. and P. Sassone-Corsi.  Heat shock interferes with steroidogenesis by reducing transcription of the StAR gene.  Molecular Endocrinology, 2001, 15(8):1255-1263.

14.   Haidan, A., Bornstein, S.R., Liu, Z., Walsh, L.P., Stocco, D.M., and M. Ehrhart-Bornstein.  Expression of adrenocortical steroidogenic acute regulatory (StAR) protein is influenced by chromaffin cells.  Molecular and Cellular Endocrinology, 2000, 165:25-32. 

15.   Sridaran, R., Philip, G.H., Li, H., Culty, M., Liu, Z., Stocco, D.M., and V. Papadopoulos.  GnRH agonist treatment decreases progesterone synthesis, luteal peripheral benzodiazepine receptor mRNA, ligand binding and steroidogenic acute regulatory protein expression during pregnancy.  Journal of Molecular Endocrinology, 1999, 22:45-54.

16.   King, S.R., Liu, Z., Soh, J., Eimerl S., Orly, J. and D.M. Stocco.  Effects of disruption of the mitochondrial electrochemical gradient on steroidogenesis and the steroidogenic acute regulatory (StAR) protein.  Journal of Steroid Biochemistry and Molecular Biology, 1999, 69:143-154. 

17.   Wang, X., Liu, Z., Eimerl, S., Timberg, R., Weiss, A.M., Orly, J. and D.M. Stocco.  Effect of truncated forms of the steroidogenic acute regulatory (StAR) protein on the intramitochondrial cholesterol transfer.  Endocrinology, 1998, 139(9):3903-3912.

18.   Liu, Z. and D.M. Stocco.  Heat shock-induced inhibition of acute steroidogenesis in MA-10 cells is associated with inhibition of the synthesis of the steroidogenic acute regulatory (StAR) protein.  Endocrinology, 1997, 138(7):2722-2728. 

19.   Arakane, F., Sugawara, T., Nishino, H., Liu, Z., Holt, J.A., Pain, D., Stocco, D.M., Miller, W.L. and J.F. Strauss, III.  Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: implications for the mechanism for StAR action.  Proceedings of the National Academy of Sciences USA, 1996, 93:13731-13736.

20.   Bosmann, H.B., Hales, K.H., Li, Xiangquan, Liu, Z., Stocco, D.M. and D.B. Hales.  Acute in vivo inhibition of testosterone by endotoxin parallels loss of steroidogenic acute regulatory (StAR) protein in Leydig cells.  Endocrinology, 1996, 137(10):4522-4525. 

21.   Liu, Z. and R. Patino.  High-affinity binding of progesterone to the plasma membrane of Xenopus oocytes: characteristics of binding and hormonal and developmental control.  Biology of Reproduction, 1993, 49:980-988.

22.   Liu, Z., Su, X.R., and Y.Y. Li.  Methods for producing biologically active substances from oyster.  State Intellectual Property Office, PRC.  2004. Patent #: ZL200410054048.7.

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